Osteochondrosis

Authors: Sheila Laverty, Christiane Girard
Journal: The Veterinary Journal

Osteochondrosis (OC) of the articular epiphyseal cartilage complex (AECC) is a developmental disease that is present in the first weeks of life. It is characterized by focal chondronecrosis and retention of growth cartilage due to failure of endochondral ossification. Fissures may extend from the lesion through the overlying articular cartilage to create a cartilage flap and an osteochondral fragment. This articular form is known as osteochondritis dissecans (OCD).

Category: Equine - Osteochondrosis
Authors: K. UpRichard , Y. A. Elce , P. Piat , G. Beauchamp , S. Laverty
Journal: Veterinary Comparative Orthopaedics and Traumatology

Objectives: To determine the short- and long-term outcome for sport horses after arthroscopic treatment of osteochondrosis of the lateral trochlear ridge of the femur. Methods: A retrospective study was performed using the medical records of horses intended for use as English sport horses. Outcome was obtained through telephone questionnaire. Results: Thirty-seven horses, mainly Warmbloods, underwent arthroscopic surgery for treatment of lateral femoral trochlear ridge osteochondrosis. Short-term outcome revealed that 27 of 37 horses had no complications.

Authors: T. Ribera, L. Monreal, M. A. Delgado, J. Ríos, M. Prades
Journal: Veterinary and Comparative Orthopaedics and Traumatology

Objective: To assess the synovial fibrinolytic pathway activation in adult horses with developmental and degenerative arthropathies such as osteochondritis dissecans (OCD) and osteoarthritis (OA) by measuring synovial D-dimer concentrations. Methods: Prospective observational clinical study of horses admitted for OCD or OA.Synovial fluid was collected during lameness examination or prior to the surgical procedure, and D-dimer concentration and routine synovial fluid analysis were performed. Results: Fifty-eight horses (14 with OCD, 10 with OA and 34 controls) were included in this study.

Authors: L. Vander Heyden, J-P. Lejeune, I. Caudron, J. Detilleux, C. Sandersen, P. Chavatte, J. Paris, B. Deliège, D. Serteyn
Journal: Veterinary Record

Osteochondrosis (OC) is the most common developmental orthopaedic disease in horses and represents a major problem to the horse industry. The complete mechanism of this multifactorial disease is not yet elucidated, but it is accepted that OC lesions are the result of intrinsic genetic and external factors. The aim of the present work was to evaluate the relationship between breeding management and OC. Breeding conditions were recorded, and a radiological examination was performed in 223 foals.

Category: Equine - Osteochondrosis
Authors: Tara L. Riddick, Katja Duesterdieck-Zellmer, Stacy A. Semevolos
Journal: Veterinary Journal

The objective of this study was to investigate the expression of several regulatory factors associated with cartilage maturation in horses with early osteochondrosis (OC) compared to normal controls. The hypothesis was that expression levels of Indian hedgehog (Ihh), parathyroid hormone-related peptide (PTH-rP), vascular endothelial growth factor (VEGF), platelet-derived growth factor-A (PDGF-A), and matrix metalloproteinase-13 and -3 (MMP-13, -3) would be increased in OC.

Category: Equine - Osteochondrosis
Authors: T. S. L. MACHADO, L. C. L. CORREIA da SILVA, R. Y. A. BACCARIN, Y. M. MICHELACCI
Journal: Equine Veterinary Journal

Reasons for performing study: Alternative methods to evaluate the joint condition in asymptomatic osteochondrosis dissecans (OCD) and other joint diseases may be useful.

Objectives: To investigate possible changes in synovial fluid composition that may lead to joint conditions in asymptomatic OCD, in mature horses.

Category: Equine - Osteochondrosis
Authors: S. LYKKJEN, K. H. ROED, N. I. DOLVIK
Journal: Equine Veterinary Journal

Reasons for performing study: Developmental orthopaedic diseases (DOD) such as osteochondrosis (OC)/osteochondrosis dissecans (OCD), palmar/plantar osteochondral fragments (POF), ununited palmar/plantar eminences (UPE) and dorsoproximal first phalanx fragments are well recognised in the horse. Aetiopathogeneses are controversial and molecular genetic screening of DNA has recently been employed for their elucidation.

Authors: L. JÖNSSON, G. DALIN, A. EGENVALL, A. NÄSHOLM, L. ROEPSTORFF, J. PHILIPSSON
Journal: Equine Veterinary Journal

Reasons for performing study: Disturbances in skeletal development, primarily osteochondrosis (OC) and palmar/plantar osseous fragments (POF), have been commonly reported as problems in young horses. However, there are few reports of such findings for epidemiological analyses or breeding purposes.

Objectives: To evaluate equine hospital data as a possible source of information for genetic evaluations by estimating prevalence and heritability of OC in the stifle, hock and fetlock joints and of POF in the fetlock.

Authors: H. D. SPARKS, A. J. NIXON, L. A. FORTIER, H. O. MOHAMMED
Journal: Equine Veterinary Journal

Reasons for performing study: Long-term efficacy of arthroscopic cartilage reattachment for the treatment of osteochondritis dissecans (OCD) lesions in the equine femoropatellar joint is unknown.

Objective: To evaluate radiographic outcome and long-term performance of horses undergoing OCD reattachment.

Hypothesis: Separated OCD cartilage flaps may be reincorporated into the joint surface by reattachment rather than flap removal.

Authors: L. C. Voute, F. M. D. Henson,D. Platt, L. B. Jeffcott,
Journal: The Veterinary Record

Lesions of the lateral trochlear ridge (LTR) of the distal femur were investigated in four pony or pony cross horses. The animals were all geldings and were six to 15 months of age. Lesions were bilateral in three ponies and unilateral in one. Femoropatellar joint effusion and lameness were present in two ponies; clinical signs were absent in the others. The proximal LTR was affected in all four animals. The radiographic appearance of the lesions was a subchondral defect containing mineralised bodies.

Category: Equine - Osteochondrosis