Biologics

OBJECTIVE: To evaluate the usefulness of laser Doppler flowmetry (LDF) to measure surface blood flow in canine cruciate ligaments, compare measurements in different sites of intact and partially ruptured canine cranial cruciate ligaments (CrCL) and intact caudal cruciate ligaments (CaCL), and investigate any association between surface blood flow in partially ruptured CrCL and synovitis or duration of clinical signs.

STUDY DESIGN: Case-controlled clinical study.

ANIMALS: Sixteen dogs with partially ruptured CrCL and five dogs with intact CrCL.

Category: Biologics - Imaging - Knee

OBJECTIVES: 1) To describe a radiographic method for determination of joint orientation lines and anatomical joint angles in orthogonal planes of feline radii; 2) to establish a range of normal radial joint orientation angles and anatomical axes in a feline population; and 3) to assess the repeatability and reliability of this methodology.

Category: Biologics - Carpus - Elbow - Imaging

OBJECTIVE: To compare the goniometric measurements of the stifle joint in seven dog breeds, and to determine the relationship among goniometric measurements, age, body weight, tibial plateau angle, crus and thigh circumferences, and widths of quadriceps, hamstring, and gastrocnemius muscles in healthy dogs.

Category: Biologics - Knee

OBJECTIVE: To assess the geometry of canine humeri as seen on radiographs in chondrodystrophic dogs (CD) and brachycephalic dogs (BD) compared to non-chondrodystrophic dogs (NCD).

METHODS: Mediolateral (ML) and craniocaudal (CC) radiographs of skeletally mature humeri were used (CD [n = 5], BD [n = 9], NCD [n = 48]) to evaluate general dimensions (length, width, canal flare, cortical thickness), curvature (shaft, humeral head, and glenoid), and angulation (humeral head and condyle). Measurements from CD, BD, and NCD were compared.

Category: Biologics

OBJECTIVE: To assess the geometry of canine humeri as seen on radiographs in chondrodystrophic dogs (CD) and brachycephalic dogs (BD) compared to non-chondrodystrophic dogs (NCD).

METHODS: Mediolateral (ML) and craniocaudal (CC) radiographs of skeletally mature humeri were used (CD [n = 5], BD [n = 9], NCD [n = 48]) to evaluate general dimensions (length, width, canal flare, cortical thickness), curvature (shaft, humeral head, and glenoid), and angulation (humeral head and condyle). Measurements from CD, BD, and NCD were compared.

Category: Biologics

OBJECTIVE: To compare the antibacterial efficacy of different surgical hand antisepsis protocols used by veterinary students.

STUDY DESIGN: Prospective, randomized, controlled study.

STUDY POPULATION: Third year veterinary students (n=45).

Category: Biologics

OBJECTIVE: To investigate the frequency, source, and risk factors of intraoperative (IO) surgeon and patient bacterial contamination during clean orthopedic surgeries, and to investigate the relationship between IO contamination and surgical site infection (SSI) in dogs.

STUDY DESIGN: Prospective clinical study.

SAMPLE POPULATION: Client-owned dogs undergoing stifle surgery (n = 100).

Category: Biologics

OBJECTIVE: To evaluate blood coagulation using thromboelastometry in dogs following orthopedic surgery.

DESIGN: Longitudinal observational study.

SETTING:  University veterinary teaching hospital.

ANIMALS:  Thirty-four adult client-owned dogs.

Category: Biologics
Authors: Minier K1, Touré A, Fusellier M, Fellah B, Bouvy B, Weiss P, Gauthier O.
Journal: VCOT

OBJECTIVES:

To determine whether the addition of recombinant human bone morphogenetic protein (rhBMP-2) to a self-crosslinkable cellulosic hydrogel/biphasic calcium phosphate (BCP) granules construct promotes bone healing in critical-size ulnar defects in dogs.

METHODS:

Authors: Walton MB1, Mardell E, Spoor M, Innes J.
Journal: VCOT

A four-year-old, male Cocker Spaniel was presented for investigation of pelvic limb stiffness. There was palpable effusion of both tarsi, and analysis of synovial fluid from these joints indicated previous haemorrhage. After further investigation a diagnosis of idiopathic immune-mediated thrombocytopenia was made. The dog responded to treatment with prednisolone and azathioprine. To the authors' knowledge, this is the first reported case of confirmed haemarthrosis as the sole presenting clinical sign for canine idiopathic immune-mediated thrombocytopenia.

Category: Biologics - Hock