Nuclear scintigraphy

Authors: H. D. O'Neill and B. M. Bladon
Journal: Veterinary Record

Records of horses admitted to a veterinary surgery in the UK for lameness investigation during 2000 to 2008 were reviewed. Twenty-one horses were identified with both scintigraphic and radiological evidence of enostosis-like lesions (ELLs), in which 68 individual foci of increased radiopharmaceutical uptake were confirmed in 57 long bones. The presenting lameness was attributed to ELLs in 15 of 21 (71 per cent) horses; the remainder were thought to be incidental findings.

Journal: Veterinary Radiology & Ultrasound

We have observed focal skeletal muscle uptake of 99mTechnetium-hydroxymethylene diphosphonate (Tc-HDP), which could mimic a tibial lesion, in horses following peroneal nerve blocks. To characterize this observation further, 45 bone phase scintigrams were performed in 12 horses undergoing peroneal nerve blocks. Scans were performed before, and 1, 3, 7, and 14 days postblock. The superficial and deep branches of the peroneal nerve were blocked by injecting 10 ml of 2% mepivacaine in one limb and 20 ml in the other.

Authors: Meehan, L.; Dyson, S.; Murray, R.
Journal: Equine Veterinary Journal

Reasons for performing study: Clinical, radiographic and scintigraphic signs associated with spondylosis of the equine thoracolumbar spine have been poorly documented.

Objectives: To establish an objective radiographic and scintigraphic grading system for spondylosis lesions; to estimate the prevalence of spondylosis in a population of horses with back pain; and to compare the results of radiography and scintigraphy

Journal: Veterinary Radiology and Ultrasound

Our aims were to evaluate the pattern of radiopharmaceutical uptake in horses with lameness related to the metacarpophalangeal and/or metatarsophalangeal joint and compare the results with similar information from sound horses. It was hypothesized that there would be a difference in radiopharmaceutical uptake between the lame and contralateral limb in unilaterally lame horses and that there would be a difference between lame and sound horses. Nuclear scintigraphic images of 43 horses with forelimb lameness and 30 horses with hindlimb lameness were evaluated.

Authors: D. Didierlaurent, MSc, V. Contremoulins, MSc, J-M. Denoix, DVM, PhD and F. Audigié, DVM, PhD
Journal: Veterinary Record

Lateral scintigraphic images of the necks of 12 show jumping horses, 12 thoroughbreds and 12 French trotters were evaluated. Custom-written automatic analysis software was used to segment the regions of the articular processes and vertebral symphyses from C3 to C7 and to calculate their mean radiopharmaceutical uptakes. The uptakes by the two sides of these sound horses were not significantly different, and the uptakes by the vertebral symphyses and articular processes were also similar in the three groups of horses, considering each vertebral level separately.

Authors: Gillen, A.; Dyson, S.; Murray, R.
Journal: Equine Veterinary Journal

Reasons for performing study: The results of nuclear scintigraphic examination of the thoracolumbar synovial intervertebral articulations (facet joints) have to date been poorly documented.

Objectives: To establish an objective scintigraphic grading system for the facet joints; to investigate the relationship between the presence or absence of clinical signs of back pain and increased radiopharmaceutical uptake (IRU); and to compare the results of scintigraphy and radiography.

Authors: C. Byron; A. Stewart; B. Benson; B. Tennent-Brown; J. Foreman
Journal: Veterinary and Comparative Orthopaedics and Traumatology

Objective: To investigate the effects of radial extracorporeal shock wave therapy (RESWT) on radiographic and scintigraphic variables in horses with clinical pain referable to the palmar heel. Methods: Eight clientowner horses with palmar heel pain were treated with RESWT for a total of three treatments. Nuclear scintigraphy and radiography were repeated at the beginning and completion of the study. Scintigram region of interest (ROI) density ratios were calculated and compared between treated limbs, untreated limbs, and a population of comparison limbs from eight horses free of lameness.

Journal: Veterinary Radiology & Ultrasound

Nuclear bone scintigraphy is commonly used in the diagnosis of sacroiliac disease in horses. The aim of the present retrospective study was to determine if there was an association between radiopharmaceutical uptake pattern and radiographic appearance of the sacroiliac region in horses. Seventy-nine horses undergoing bone scintigraphy with Tc-99 m-HDP and radiography of the pelvis because of lameness or poor performance were studied. Subjective and semiquantitative methods were used to characterize and compare radiopharmaceutical uptake between horses.

Authors: Dyson, S.; Blunden, T.; Murray, R.
Journal: Equine Veterinary Journal

Reasons for performing study: Magnetic resonance imaging (MRI) is used with increasing frequency to diagnose injuries of the collateral ligaments (CLs) of the distal interphalangeal (DIP) joint, but the results have not been verified by histology and the mechanism of injury is poorly understood. Hypothesis: Abnormal signal intensity and tissue contour represents change in tissue structure detected on histology. Objectives: To compare results in horses free from and those with chronic lameness and to describe possible progression of lesions.

Authors: Jonathan D. C. Anderson, BVM&S; Larry D. Galuppo, DVM, DACVS; Bradd C. Barr, DVM, DACVP; Sarah M. Puchalski, DVM, DACVR; Melinda
Journal: Journal of the American Veterinary Medical Association

Objective—To describe clinical and scintigraphic abnormalities in horses with a bone fragility disorder. Design—Retrospective case series. Animals—16 horses with scintigraphic evidence of multiple sites of increased radiopharmaceutical uptake (IRU). Procedures—Medical records were reviewed for information on signalment; history; clinical, clinicopathologic, and diagnostic imaging findings; and treatment. Follow-up information was obtained through telephone interviews with owners. Results—Horses ranged from 4 to 22 years old; there were 8 castrated males and 8 females.