Bone

Authors: Wade T. Walker, Christopher E. Kawcak, Ashley E. Hill
Journal: American Journal of Veterinary Research

Objective—To characterize medial femoral condyle (MFC) morphometrics and subchondral bone density patterns in Thoroughbred racehorses and to determine whether these variables differ between left and right limbs.

Sample—Stifle joints harvested from 6 Thoroughbred racehorses euthanized for reasons other than hind limb lameness.

Category: Bone - Equine
Authors: M. K. Adams, L. R. Goodrich, S. Rao, F. Olea-Popelka, N. Phillips, J. D. Kisiday and C. W. Mcilwraith
Journal: Equine Veterinary Journal

Summary

Reasons for performing study

The 2 sites of bone marrow harvest for isolation of mesenchymal stromal cells (MSC) in the horse are the sternum and ilium. The technical procedure is based on practitioner preference, but no studies have compared MSC concentrations and growth rates between the sites in horses aged 2–5 years.

Objectives

Category: Bone - Equine - Stem cells
Authors: S. A. Vallance, R. C. Entwistle, P. L. Hitchens, I. A. Gardner and S. M. Stover
Journal: Equine Veterinary Journal

Summary

Reasons for performing study:

Identification of exercise history patterns that are related to catastrophic scapular fracture will facilitate prevention of racehorse fatalities.

Objectives:

To determine if exercise patterns are associated with scapular fracture in Thoroughbred (TB) and Quarter Horse (QH) racehorses.

Methods:

Authors: L. M. S. O'Hare, P. G. Cox, N. Jeffery and E. R. Singer
Journal: Equine Veterinary Journal

Summary

Reasons for performing study

To improve understanding of the internal structure of the proximal phalanx (P1), response of the bone to load and possible relation to the pathogenesis of fractures in P1.

Objectives

To model the P1 and replicate the loads experienced by the bone in stance, walk, trot and gallop using finite element analysis.

Methods

Category: Bone - Equine
Authors: M. S. Madron, S. R. McClure and M. Yaeger
Journal: Equine Veterinary Education

Summary

Category: Bone - Case study - Equine
Authors: Jorge E. Nieto, MVZ, PhD; Omar Maher, DVM; Scott D. Stanley, PhD; Heather K. Knych, DVM, PhD; Jack R. Snyder, DVM, PhD
Journal: American Journal of Veterinary Research

Objective—To determine the pharmacokinetics, pharmacodynamics, and safety of zoledronic acid in horses.

Animals—8 healthy horses.

Category: Bone - Equine - Treatment
Authors: Naoki Sasaki, Satoru Nishii, Kazutaka Yamada, Hidehumi Huruoka, Yasuhiko Tabata
Journal: Journal of Equine Veterinary Science

Our objective in this study was to examine the effect of gelatin hydrogel (GH) sheets containing basic fibroblast growth factor (bFGF) on healing of proximal sesamoid bone transverse fractures in the horse. Ten healthy adult Thoroughbreds were used. The lateral proximal sesamoid bone of the left forelimb and the medial proximal sesamoid bone of the right forelimb were osteotomized, while the horses were under general anesthesia, and subsequently repaired by lag screw fixation using a single 4.5-mm cortical screw.

Category: Bone - Equine
Authors: Imke Janssen, Jan-Hein Swagemakers, Marc Koene, Christoph Lischer
Journal: Journal of Equine Veterinary Science

This case report demonstrates the development and management of an osseous cyst-like lesion in the spongiosa of the navicular bone in a high-level show jumper with chronic intermittent forelimb lameness. The first evidence of navicular bone pathology was increased signal intensity on fat-suppressed images in the medulla of the right navicular bone, which progressed to a cystic lucency identified on radiographs at 24 months.

Category: Bone - Case study - Equine - MRI
Authors: Sue Dyson
Journal: Journal of Equine Veterinary Science

The clinical features, response to local analgesia, and imaging findings of two mature sport horses with lameness associated with abnormal mineralization of the dorsal aspect of the central tarsal bone and a small osseous cyst-like lesion are described. Although the radiological findings and the lesions identified using magnetic resonance imaging were similar, the lameness characteristics and responses to perineural analgesia differed. One horse failed to respond to treatment and was retired. The second horse was humanely destroyed.

Category: Bone - Case study - Equine
Authors: Julien Olive, DMV, MSc; Thibault Vila, DMV; Nicolas Serraud, DMV
Journal: American Journal of Veterinary Research

Objective—To compare navicular bone marrow lesion (BML) conspicuity in the feet of horses as determined via 2 fat-suppressed MRI techniques, including standard short tau inversion recovery (STIR) and inversion recovery gradient echo (IRGE).

Sample—Feet (n = 150) of horses with lameness referable to the distal portion of the digit.

Category: Bone - Equine - Imaging - MRI